Cold Therapy

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Inspiration

Since the Nobel Prize-winning work of David Julius and Ardem Patapoutian in 2021 “for their discoveries of receptors for temperature and touch.” Further explains the effects and mechanisms of temperature on our body.

Cooling is clinically proven to reduce pain, itchiness, and inflammation. It also trigger a physiological healing response in the body. Letting you do more, recover and feel better.

COOLING helps Reduce Inflammation and Ease Itchiness

31.6m

31.6 million people (10.1%) in the U.S. have some form of eczema, and prevalence peaks during early childhood.

1 in 10

It is estimated that 1 in 10 individuals will develop eczema during their lifetime, with prevalence peaking in early childhood.

12 hours per day

60.5% of adults with moderate to severe AD have reported severe or unbearable itch in the past two weeks, 86% reported daily itch and 63% reported itching at least 12 hours per day.

Cooling Effects on Skin

Normal Skin

Flared up Skin

Cooling physically cause blood vessels to constrict but also act as a stimulus to distract you from pain and itchiness.

Scientific articles:

Cooling Relief of Acute and Chronic Itch Requires TRPM8 Channels and Neurons.Palkar R, Ongun S, Catich E, Li N, Borad N, Sarkisian A, McKemy DD.

Cooling the Itch via TRPM8.Liu B, Jordt SE.

Pain-free Dermatology: Minimizing Discomfort in Procedures for Children and Adults

Peter A. Lio, MD and Alisa A. McQueen, MD

Cooling Effects on Cells

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RELIEVE

Exposure to cold is known to activate the sympathetic nervous system and increase the blood level of beta-endorphin and noradrenaline and to increase synaptic release of noradrenaline in the brain as well. Leading to a happier state of mind.

REPAIR

There is evidence that cold therapy improves mitochondrial health through a process known as “mitochondrial biogenesis,” or in other words, by producing more of them. Cold therapy can be compelling because it forces you to become comfortable with discomfort.

REDUCE & RELAX

Cold slows blood flow, reducing swelling and pain. Reduces inflammation by decreasing blood flow.

Cold Effects on Blood Vessels

Cold Effects on Pores

The Best Skin Secrets

https://www.vogue.com/article/ice-cubes-best-skincare-trick-pore-shrinking-acne-cure-beauty-benefits

Heals and prevent Acne

Healthy Glow

Reduces Puffy Eyes

Anti Ageing

Shrinks the Pores

Pre-condition your face for primer

Should You Be Putting Ice on Your Face? Experts Say Yes

How do I remedy the painful eczema irritation?

https://newsnetwork.mayoclinic.org/discussion/home-remedies-relieve-and-reduce-itchy-eczema/

Cooling Relief of Acute and Chronic Itch Requires TRPM8 Channels and Neurons

https://www.sciencedirect.com/science/article/pii/S0022202X1733364X

Cooling the Itch via TRPM8 - PMC - NCBI

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301073/

HOW TO RELIEVE ITCHY SKIN

https://www.aad.org/public/everyday-care/itchy-skin/itch-relief/relieve-itchy-skin

How to relieve itching

https://www.medicalnewstoday.com/articles/323491

QOOLMATE is designed to medical device standards IEC 60601 but has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.